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Recombinant Cynomolgus FcRN Protein

Recombinant Cynomolgus Beta-2-microglobulin&IgG Receptor FcRn Large Subunit P51 is produced by our Mammalian expression system and the target gene encoding Ile21-Met119&Ala24-Ser297 is expressed with a Flag tag at the C-terminus, 6His tag at the C-terminus.

Product Specifications

Product Name Alternative

IgG receptor FcRn; Neonatal Fc receptor; FCRN

UniProt

Q8SPW0, Q8SPV9

Expression Region

Ile21-Met119&Ala24-Ser297

Conjugation

Unconjugated

Tag

C-Flag-6His

Origin

Cynomolgus

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Recombinant Cynomolgus FcRn Heterodimer (C-6His) (Cat#orb2994891) on HIS1K Biosensor, can bind Anti-Human HER2 mAb (Cat#GMP-A062) with an affinity constant of 11.1 nM as determined in BLI assay. (Regularly tested)

Form

Lyophilized

Molecular Weight

Predicted: 12.6&31.3 KDa. Observed: 14&33 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

Available Sizes

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