Recombinant Cynomolgus IL-4RA Protein
Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Met26-Arg232 is expressed with a human IgG1 Fc tag at the C-terminus.
Product Specifications
Product Name Alternative
Interleukin-4 receptor subunit alpha; IL-4R-alpha; CD124; IL4-BP; Soluble IL-4R-alpha
UniProt
G7Q0S7
Expression Region
Met26-Arg232
Conjugation
Unconjugated
Tag
C-Fc
Origin
Cynomolgus
Field of Research
Immunology & Inflammation
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Human IL-4-His (Cat#orb3002435) on HIS1K Biosensor, can bind Cynomolgus IL-4RA-Fc (Cat#orb2993918) with an affinity constant of 0.03 nM as determined in BLI assay. . Cell Based Assay: Measured by its ability to inhibit IL-4-dependent proliferation of TF‐1 human erythroleukemic cells.The ED50 for this effect is 6.02 ng/ml.
Form
Lyophilized
Molecular Weight
Predicted: 50.7 KDa. Observed: 65-90 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of 20mM Tris-HCl, 100mM Glycine, pH 7.5.
Available Sizes
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