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Recombinant Cynomolgus IL-4RA Protein

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Met26-Arg232 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Interleukin-4 receptor subunit alpha; IL-4R-alpha; CD124; IL4-BP; Soluble IL-4R-alpha

UniProt

G7Q0S7

Expression Region

Met26-Arg232

Conjugation

Unconjugated

Tag

C-Fc

Origin

Cynomolgus

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Human IL-4-His (Cat#orb3002435) on HIS1K Biosensor, can bind Cynomolgus IL-4RA-Fc (Cat#orb2993918) with an affinity constant of 0.03 nM as determined in BLI assay. . Cell Based Assay: Measured by its ability to inhibit IL-4-dependent proliferation of TF‐1 human erythroleukemic cells.The ED50 for this effect is 6.02 ng/ml.

Form

Lyophilized

Molecular Weight

Predicted: 50.7 KDa. Observed: 65-90 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of 20mM Tris-HCl, 100mM Glycine, pH 7.5.

Available Sizes

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