Recombinant Human IL-23 Protein
Recombinant Human Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328&Ala21-Pro189 is expressed with a human IgG1 Fc tag at the C-terminus.
Product Specifications
Product Name Alternative
SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2
UniProt
Q9NPF7, P29460
Expression Region
Ile23-Ser328&Ala21-Pro189
Conjugation
Unconjugated
Tag
C-Fc
Origin
Human
Field of Research
Immunology & Inflammation
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
ELISA: Immobilized Human IL-23R-His (Cat#orb2994303) at 5μg/ml (100 μl/well) can bind Human IL-23-Fc (Cat#orb2993914) .The ED50 of Human IL-23-Fc (Cat#orb2993914) is 0.187 ug/ml.. Cell Based Assay: Measured by its ability to induce STAT reporter activity in 293F human embryonic kidney cells. The ED50 for this effect is 179.42 ng/ml.
Form
Lyophilized
Molecular Weight
Predicted: 81.3 KDa. Observed: 80-110 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Available Sizes
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