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Recombinant Cynomolgus SIRPA Protein

Recombinant Cynomolgus Signal-Regulatory Protein Alpha 1 is produced by our Mammalian expression system and the target gene encoding Glu31­Arg369 is expressed with a 6His tag at the C-terminus.

Product Specifications

Product Name Alternative

Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; SHP Substrate 1; SHPS-1; Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs; Bit; CD172 Antigen-Like Family Member A; Inhibitory Feceptor SHPS-1; Macrophage Fusion Receptor; MyD-1 Antigen; Signal-Regulatory Protein Alpha-1; Sirp-Alpha-1; Signal-Regulatory Protein Alpha-2; Sirp-Alpha-2; Signal-Regulatory Protein Alpha-3; Sirp-Alpha-3; p84; CD172a; SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP

UniProt

I7G9Z7

Expression Region

Glu31­Arg369

Conjugation

Unconjugated

Tag

C-6His

Origin

Cynomolgus

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Anti-Human SIRPA mAb-Fc (Cat#orb2993142) on Protein A Biosensor, can bind Cynomolgus SIRPA-His (Cat#orb2993876) with an affinity constant of 30.3 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 37.9 KDa. Observed: 50-75 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

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