Antibacterial agent 180

Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) [1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-180.html

Solubility

10 mM in DMSO

Smiles

O=[N+]([O-])C1=NN(C=N1)CC2=CN(N=N2)C3=CC=C(C=C3)OC(F)(F)F

Molecular Formula

C12H8F3N7O3

Molecular Weight

355.23

References & Citations

[1]Bruno I Pelizaro, et al. Design and Synthesis of Novel 3-Nitro-1 H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis. J Med Chem. 2024 Feb 22;67 (4) :2584-2601.