Antibacterial agent 180
Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) [1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-180.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])C1=NN(C=N1)CC2=CN(N=N2)C3=CC=C(C=C3)OC(F)(F)F
Molecular Formula
C12H8F3N7O3
Molecular Weight
355.23
References & Citations
[1]Bruno I Pelizaro, et al. Design and Synthesis of Novel 3-Nitro-1 H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis. J Med Chem. 2024 Feb 22;67 (4) :2584-2601.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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