Recombinant Human HER3 Protein
Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Thr643 is expressed with a mouse IgG1 Fc tag at the C-terminus.
Product Specifications
Product Name Alternative
Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3
UniProt
P21860
Expression Region
Ser20-Thr643
Conjugation
Unconjugated
Tag
C-mFc
Origin
Human
Field of Research
Signal Transduction
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Human NRG1Beta (245AA) (Cat#orb3002365) on APS Biosensor, can bind Human HER3-mFc (Cat#orb2993801) with an affinity constant of 3.6 nM as determined in BLI assay. Loaded Human NRG1Beta (246AA) (Cat#CH84) on APS Biosensor, can bind Human HER3-mFc (Cat#orb2993801) with an affinity constant of 4.3 nM as determined in BLI assay.
Form
Lyophilized
Molecular Weight
Predicted: 95.1 KDa. Observed: 120-135 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4.
Available Sizes
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