Recombinant Mouse IL-17A Protein
Recombinant Mouse Interleukin-17A is produced by our Mammalian expression system and the target gene encoding Thr22-Ala158 is expressed with a 6His tag at the C-terminus.
Product Specifications
Product Name Alternative
Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; IL17A; CTLA8; IL17
UniProt
Q62386
Expression Region
Thr22-Ala158
Conjugation
Unconjugated
Tag
C-6His
Origin
Mouse
Field of Research
Immunology & Inflammation
Endotoxin
< 0.01 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Biotinylated Human IL-17RA -His-Avi (Cat#orb2993686) on SA Biosensor, can bind Mouse IL-17A-His (Cat#orb2994008) with an affinity constant of 12.6 nM as determined in BLI assay.. Cell Based Assay: Measured by its ability to induce IL-6 secretion by NIH‐3T3 mouse embryonic fibroblast cells.The ED50 for this effect is 0.25-1.25 ng/ml. (QC verified)
Form
Lyophilized
Molecular Weight
Predicted: 16.2 KDa. Observed: 17-26 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4.
Available Sizes
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