Recombinant Human ICOS Protein

Recombinant Human Inducible T-cell Costimulator is produced by our Mammalian expression system and the target gene encoding Glu21-Phe141 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1; ICOS

UniProt

Q9Y6W8

Expression Region

Glu21-Phe141

Conjugation

Unconjugated

Tag

C-Fc

Origin

Human

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Recombinant Human ICOSLG (C-6His) (Cat#orb2995052) on HIS1K Biosensor, can bind Recombinant Human ICOS (C-Fc) (Cat#orb2994712) with an affinity constant of 9.56 nM as determined in BLI assay. (Regularly tested)

Form

Lyophilized

Molecular Weight

Predicted: 40.9 KDa. Observed: 47 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.