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Recombinant Human IL-17A&17F Protein

Recombinant Human Interleukin-17A/Interleukin-17F Heterodimer is produced by our Mammalian expression system and the target gene encoding Gly24-Ala155&Arg31-Gln163 is expressed with a 6His tag at the C-terminus.

Product Specifications

Product Name Alternative

IL‐17A/F Heterodimer; IL-17A&IL-17F Heterodimer

UniProt

Q16552

Expression Region

Gly24-Ala155&Arg31-Gln163

Conjugation

Unconjugated

Tag

C-6His

Origin

Human

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.. SEC-HPLC: Greater than 95% as determined by SEC-HPLC. (QC verified)

Bioactivity

BLI: Loaded Biotinylated Human IL-17RA -His-Avi (Cat#orb2993686) on SA Biosensor, can bind Human IL-17A&17F-His (Cat#orb2994531) with an affinity constant of 8.6 pM as determined in BLI assay. Loaded Biotinylated Human IL-17RA-Fc (Cat#orb2993676) on Pro A Biosensor, can bind Human IL-17A&17F-His (Cat#orb2994531) with an affinity constant of 10.3 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 15.1&16 KDa. Observed: 15-25 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.

Available Sizes

Frequently Asked Questions

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