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Recombinant Human IL-23R Protein

Recombinant Human Interleukin-23 Receptor is produced by our Mammalian expression system and the target gene encoding Gly24-Asp353 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Interleukin-23 receptor; IL23R; IL-23 receptor; IL-23R

UniProt

Q5VWK5

Expression Region

Gly24-Asp353

Conjugation

Unconjugated

Tag

C-Fc

Origin

Human

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 90% as determined by reducing SDS-PAGE.

Bioactivity

ELISA: Immobilized Human IL-23R-Fc (Cat#orb2994313) at 10μg/ml (100 μl/well) can bind Human IL-23-His (Cat#orb2993911) .The ED50 of Human IL-23-His (Cat#orb2993911) is 0.248 ug/ml.. BLI: Loaded Human IL-23R-Fc (Cat#orb2994313) on Protein A Biosensor, can bind Mouse IL-23A (Cat#orb2993830) with an affinity constant of 3.81 nM as determined in BLI assay. (Regularly tested) Loaded Human IL-23R-Fc (Cat#orb2994313) on Protein A Biosensor, can bind Mouse IL-23A (Cat#orb2994552) with an affinity constant of 1.7 nM as determined in BLI assay. (Regularly tested)

Form

Lyophilized

Molecular Weight

Predicted: 65 KDa. Observed: 90-120 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

Available Sizes

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