Recombinant Human IL-4 RA Protein

Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

BLI: Loaded Dupilumab on Pro-A Biosensor, can bind Recombinant Human IL-4 RA (C-6His) (Cat#orb2994200) with an affinity constant of 1.78 nM as determined in BLI assay. (Regularly tested) Loaded Human IL-4-Fc (Cat#orb3002348) on Protein A Biosensor, can bind Human IL-4 RA-His (Cat#orb2994200) with an affinity constant of 0.78 nM as determined in BLI assay. . Cell Based Assay: Measured by its ability to inhibit IL-4-dependent proliferation of TF‐1 human erythroleukemic cells.The ED50 for this effect is 5-20 ng/ml. (QC verified)

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.