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Goat anti-MAP2K2 / MEK2 Antibody

Goat polyclonal antibody to MAP2K2 which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family. It highly expressed in the neonatal brain. It catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MAP2K2 activates the ERK1 and ERK2 MAP kinases. Genetic variation in MAP2K2 are a cause of cardiofaciocutaneous syndrome.

Product Specifications

Product Name Alternative

Anti MAP2K2 antibody, anti mitogen-activated protein kinase kinase 2 antibody, anti MAPKK2 antibody, anti MEK2 antibody, anti MKK2 antibody, anti PRKMK2 antibody, anti ERK activator kinase 2 antibody, anti MAP kinase kinase 2 antibody, anti MAPK/ERK kinase 2 antibody, anti dual specificity mitogen-activated protein kinase kinase 2 antibody, anti mitogen-activated protein kinase kinase 2, p45 antibody

Reactivity

Human

Target

MAP2K2 / MEK2

Clonality

Polyclonal

Conjugation

Unconjugated

Sequence

DLKMLTNHTFIKRS

Field of Research

Cell Biology

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Dilution

ELISA: 1:128000, WB: 0.1-0.3 μg/ml

Molecular Weight

44,4

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: Approx 48kDa band observed in lysates of cell lines Daudi, Jurkat, K562 and Molt4 (calculated MW of 44.4kDa according to NP_109587.1) . Recommended concentration: 0.1-0.3 μg/ml.

Tested Applications

ELISA, WB

Preservative

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Entrez

5605

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