Sodium orthovanadate
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.
Product Specifications
CAS Number
[13721-39-6]
UNSPSC
12352200
Hazard Statement
H302+H312+H332, H315, H319
Target
Phosphatase
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Sodium-orthovanadate.html
Purity
99.00
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 8 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[O].[Na].[V]
Molecular Formula
Na3O4V
Molecular Weight
183.91
Precautions
H302+H312+H332, H315, H319
References & Citations
[1]Gordon JA, et al. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol. 1991;201:477-82.|[2]Wu DN, et al. Down-regulation of PTEN by sodium orthovanadate inhibits ASK1 activation via PI3-K/Akt during cerebral ischemia in rat hippocampus. Neurosci Lett. 2006 Aug 14;404 (1-2) :98-102.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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