Tyrosinase-IN-35
Tyrosinase-IN-35 (compound 6g) is a human tyrosinase inhibitor (IC50: 2.09 μM), which is more potent than Kojic Acid (IC50: 16.38 μM). Tyrosinase-IN-35 can reduce the melanin content of melanoma B16F10 cells in vitro at doses of 4 μM and 8 μM[1].
Product Specifications
CAS Number
1613467-47-2
UNSPSC
12352005
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-35.html
Smiles
OC1=CC=C(C2=NN(C3=CC=CC=C3)C=C2/C=N\NC(N)=S)C=C1
Molecular Formula
C17H15N5OS
Molecular Weight
337.40
References & Citations
[1]Kinetic studies, molecular docking, and antioxidant activity of novel 1,3-diphenyl pyrazole-thiosemicarbazone with anti-tyrosinase and anti-melanogenesis properties
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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