Diazaborine
Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL[1].
Product Specifications
CAS Number
22959-81-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/diazaborine.html
Purity
98.01
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=S(N1B(C2=CC=CC=C2C=N1)O)(C3=CC=C(C)C=C3)=O
Molecular Formula
C14H13BN2O3S
Molecular Weight
300.14
References & Citations
[1]Jordan CA, et al., Crystallographic insights into the structure-activity relationships of diazaborine enoyl-ACP reductase inhibitors. Acta Crystallogr F Struct Biol Commun. 2015 Dec;71 (Pt 12) :1521-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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