L-Ascorbic acid-d2
Product Specifications
UNSPSC Description
L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
Target Antigen
Apoptosis; Calcium Channel; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB;Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC([C@@]1([H])[C@H](C([2H])([2H])O)O)=C(O)C(O1)=O
Molecular Weight
178.14
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.;Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
82977-10-4
Available Sizes
Curated Selection
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