Recombinant Human FcRn Heterodimer Protein
Recombinant Human IgG Fc Fragment Receptor Transporter is produced by our Mammalian expression system and the target gene encoding Ala24-Ser297&Ile21-Met119 is expressed with a 6His tag at the C-terminus.
Product Specifications
Product Name Alternative
IgG receptor FcRn; Neonatal Fc receptor; FCRN
UniProt
P61769
Expression Region
Ala24-Ser297&Ile21-Met119
Conjugation
Unconjugated
Tag
C-6His
Origin
Human
Endotoxin
<0.1EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.. SEC-HPLC: Greater than 95% as determined by SEC-HPLC. (QC verified)
Bioactivity
BLI: Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Anti-Human HER2 mAb (Human IgG1) (Cat#GMP-A062) with an affinity constant of 11.3 nM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Anti-Human CD137 mAb (Human IgG4) (Cat#orb2993114) with an affinity constant of 0.376 uM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG1 Fc (Cat#orb2993960) with an affinity constant of 98.6 nM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG1 Fc (Cat#orb2992939) with an affinity constant of 0.265 uM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG2 Fc (223AA) (Cat#orb2993943) with an affinity constant of 85.7 nM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG2 Fc (228AA) (Cat#orb2993938) with an affinity constant of 74.5 nM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG3 Fc (Cat#orb2993894) with an affinity constant of 0.101 uM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG4 Fc (228AA) (Cat#orb2993937) with an affinity constant of 0.127 uM as determined in BLI assay. (Regularly tested) Loaded Recombinant Human FcRn Heterodimer (C-6His) (Cat#orb2994565) on HIS1K Biosensor, can bind Recombinant Human IgG4 Fc (224AA) (Cat#orb2993942) with an affinity constant of 48 nM as determined in BLI assay. (Regularly tested)
Form
Lyophilized
Molecular Weight
Predicted: 31.2&11.7 KDa. Observed: 37&13 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.4.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402848-500 1x 500 µL
Fibronectin (Fn-3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details