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Recombinant Cynomolgus BCMA Protein

Recombinant Cynomolgus B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala53 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma

UniProt

G7Q0I4

Expression Region

Met1-Ala53

Conjugation

Unconjugated

Tag

C-Fc

Origin

Cynomolgus

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

ELISA: Immobilized Human APRIL -Flag-His (Cat#orb2994084) at 1μg/ml (100 μl/well) can bind Cynomolgus BCMA-Fc (Cat#orb2994273) .The ED50 of Cynomolgus BCMA-Fc (Cat#orb2994273) is 4.23 ng/ml.. BLI: Loaded Human APRIL-His (Cat#orb2994084) on HIS1K Biosensor, can bind Cynomolgus BCMA-Fc (Cat#orb2994273) with an affinity constant of 0.54 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 33.1 KDa. Observed: 38-45 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.

Available Sizes

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