Recombinant Human TIGIT Protein
Recombinant Human T-cell Immunoreceptor With Ig And ITIM Domains is produced by our Mammalian expression system and the target gene encoding Met22-Pro141 is expressed with a human IgG1 Fc tag at the C-terminus.
Product Specifications
Product Name Alternative
T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3; Tigit; VSIG9; VSTM3
UniProt
Q495A1
Expression Region
Met22-Pro141
Conjugation
Unconjugated
Tag
C-Fc
Origin
Human
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Recombinant Mouse PVR (C-6His) (Cat#orb2992802) on HIS1K Biosensor, can bind Recombinant Human TIGIT (C-Fc) (Cat#orb2994151) with an affinity constant of 17.6 nM as determined in BLI assay. (Regularly tested) Loaded Human PVR-His (Cat#orb2993514) on HIS1K Biosensor, can bind Human TIGIT-Fc (Cat#orb2994151) with an affinity constant of 8.58 nM as determined in BLI assay.
Form
Lyophilized
Molecular Weight
Predicted: 39.7 KDa. Observed: 40-55 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4.
Available Sizes
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