Hydroxyfasudil (hydrochloride)
Hydroxyfasudil hydrochloride is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively.
Product Specifications
CAS Number
155558-32-0
Product Name Alternative
HA-1100 hydrochloride; HA 1100 hydrochloride; HA1100 hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Hydroxyfasudil-hydrochloride.html
Purity
98.99
Solubility
DMSO : 30 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC=CC2=C1C=CC=C2S(=O)(N3CCNCCC3)=O.[H]Cl
Molecular Formula
C14H18ClN3O3S
Molecular Weight
343.83
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
ROCK1; ROCK2
Available Sizes
Frequently Asked Questions
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