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Recombinant Human SIRPA Protein

Recombinant Human Signal-Regulatory Protein Alpha-1 is produced by our Mammalian expression system and the target gene encoding Glu31-Arg370 is expressed with a mouse IgG2a Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; Signal-regulatory protein alpha-1; p84; CD172a; SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP

Expression Region

Glu31-Arg370

Conjugation

Unconjugated

Tag

C-mIgG2a Fc

Origin

Human

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Anti-Human SIRPA mAb-Fc (Cat#orb2993142) on AHC Biosensor, can bind Human SIRPA-mIgG2aFc (Cat#orb2994542) with an affinity constant of 0.14 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 64.5 KDa. Observed: 80-120 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4.

Available Sizes

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