Bromperidol (hydrochloride)

Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill Mycobacteria in a synergistic manner with Spectinomycin[1][2].

Product Specifications

CAS Number

[59453-24-6]

Product Name Alternative

R-11333 (hydrochloride)

UNSPSC

12352005

Target

Bacterial; Dopamine Receptor

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bromperidol-hydrochloride.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(CCCN1CCC(C2=CC=C(C=C2)Br)(CC1)O)C3=CC=C(C=C3)F.Cl

Molecular Formula

C21H24BrClFNO2

Molecular Weight

456.78

References & Citations

[1]Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35 (6) :670-84.|[2]Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55 (8) :3861-9.