Bromperidol (hydrochloride)
Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill Mycobacteria in a synergistic manner with Spectinomycin[1][2].
Product Specifications
CAS Number
[59453-24-6]
Product Name Alternative
R-11333 (hydrochloride)
UNSPSC
12352005
Target
Bacterial; Dopamine Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bromperidol-hydrochloride.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(CCCN1CCC(C2=CC=C(C=C2)Br)(CC1)O)C3=CC=C(C=C3)F.Cl
Molecular Formula
C21H24BrClFNO2
Molecular Weight
456.78
References & Citations
[1]Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35 (6) :670-84.|[2]Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55 (8) :3861-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
D2 Receptor
Available Sizes
Curated Selection
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