HIV-1 inhibitor-64
HIV-1 inhibitor-64 (Compound 7c) is a wild-type HIV-1 inhibitor that effectively suppresses the activity of HIV-1 mutants E138K/Q148K and G140S/Q148R with EC50 values of 62.5 nM and 11.3 nM, respectively. HIV-1 inhibitor-64 exhibits antiviral activity and can be used in the research of AIDS[1].
Product Specifications
CAS Number
[2919019-36-4]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-64.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C(C)C)CCN1C=C2C(NCC3=C(F)C=C(F)C=C3)=O)C1=C(O)C2=O
Molecular Formula
C19H19F2N3O4
Molecular Weight
391.37
References & Citations
[1]Mahajan, et al. "N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants." ACS Infectious Diseases (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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