Hexadecanal

Hexadecanal (Palmitaldehyde), a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal (OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression[1][2][3]

Product Specifications

CAS Number

[629-80-1]

Product Name Alternative

Palmitaldehyde

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hexadecanal.html

Purity

98.87

Solubility

DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCC=O

Molecular Formula

C16H32O

Molecular Weight

240.42

Precautions

H315, H319

References & Citations

[1]Gilbertson JR, et al. Isolation and analysis of free fatty aldehydes from rat, dog, and bovine heart muscle. J Lipid Res. 1967 Jan;8 (1) :38-45.|[2]Mishor E, et al. Sniffing the human body volatile hexadecanal blocks aggression in men but triggers aggression in women[J]. Sci Adv. 2021 Nov 19;7 (47) :eabg1530. |[3]Jaffuel G, et al. Potent Ant Deterrents Emitted from Nematode-Infected Insect Cadavers[J]. J Chem Ecol. 2022 Jan;48 (1) :71-78.