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GLPG3970

GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease[1].

Product Specifications

CAS Number

[2403733-82-2]

UNSPSC

12352005

Target

Salt-inducible Kinase (SIK)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/glpg3970.html

Concentration

10mM

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=C(CCN1CC(F)(F)F)C=C(C3=CN=C4C=C(C=CN43)OCCN5CCOCC5)C=C2OC

Molecular Formula

C25H27F3N4O4

Molecular Weight

504.50

References & Citations

[1]DESROY N, et al. NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES. WO/2019/238424. 2019.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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