Brodimoprim

Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria[1].

Product Specifications

CAS Number

[56518-41-3]

Product Name Alternative

Ro 10-5970

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/brodimoprim.html

Purity

99.36

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

COC1=C(C(OC)=CC(CC2=CN=C(N=C2N)N)=C1)Br

Molecular Formula

C13H15BrN4O2

Molecular Weight

339.19

References & Citations

[1]Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5 (6) :475-479.|[2]Marchese A, et al. Brodimoprim: effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability. J Chemother. 1996;8 (3) :171-177.