Brodimoprim
Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria[1].
Product Specifications
CAS Number
[56518-41-3]
Product Name Alternative
Ro 10-5970
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/brodimoprim.html
Purity
99.36
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
COC1=C(C(OC)=CC(CC2=CN=C(N=C2N)N)=C1)Br
Molecular Formula
C13H15BrN4O2
Molecular Weight
339.19
References & Citations
[1]Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5 (6) :475-479.|[2]Marchese A, et al. Brodimoprim: effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability. J Chemother. 1996;8 (3) :171-177.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under argon)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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