Purified Anti-Human CD61 Antibody[VI-PL2]
Product Specifications
Background
CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
Abbreviation
CD61
Gene ID
3690
UniProt
P05106
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD61 protein
Target
ITGB; BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT; Integrin beta 3; ITGB3; Integrin beta-3; &beta-3 integrin-n; beta subunit; CD 61; CD61 antigen; HPA 1; HPA 4; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) ; Integrin beta chain beta 3; ITB3; ITG B3; ITGB 3; ITG-B3; NAIT; Platelet fibrinogen receptor; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; Platelet glycoprotein IIIa precursor; Platelet Membrane Glycoprotein IIIa; PTP
Clonality
Monoclonal
Clone
VI-PL2
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cardiovascular; Signal Transduction; Immunology; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/1cxeq9
Product MSDS
https://789.bio/eb/t1KV9C
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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