CP-84364
Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25 μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities.
Product Specifications
CAS Number
114457-62-4
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cp-84364.html
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NC(N2CCOCC2)=O
Molecular Formula
C14H18N2O4
Molecular Weight
278.30
References & Citations
[1]Quantitation of 4-cyclohexyl-2-hydroxy-3- (3-methylsulfanyl-2-{2- [ (morpholine-4-carbonyl) amino]-3- phenylpropionylamino}propionylamino) butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[ (morpholine-4-carbonyl) amino]-3-phenylpropionic acid (CP-84,364) in dog and human plasma by high-performance liquid chromatography
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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