(S, R, S) -AHPC-PEG2-NH2 (hydrochloride)
(S, R, S) -AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S) -AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
2097973-72-1
Product Name Alternative
VH032-PEG2-NH2 (hydrochloride) ; VHL Ligand-Linker Conjugates 3 (hydrochloride) ; E3 ligase Ligand-Linker Conjugates 6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_6.html
Purity
99.77
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 175 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
Molecular Formula
C28H42ClN5O6S
Molecular Weight
612.18
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Available Sizes
Frequently Asked Questions
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