Gly-Gly-Gly-PEG2-azide
Gly-Gly-Gly-PEG2-azide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2222277-20-3]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gly-gly-gly-peg2-azide.html
Purity
95.00
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[N-]=[N+]=NCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O
Molecular Formula
C12H23N7O5
Molecular Weight
345.35
References & Citations
[1]Xu Y, et, al. A kind of preparation method of antibody coupling medicine, antibody coupling medicine and application. CN107875398A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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