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(S) -p-SCN-Bn-DOTA

(S) -p-SCN-Bn-DOTA is a bifunctional chelator (BFC), a macrocyclic DOTA derivative for tumor pretargeting. (S) -p-SCN-Bn-DOTA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies[1].

Product Specifications

CAS Number

[1020407-41-3]

UNSPSC

12352200

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-p-scn-bn-dota.html

Purity

99.75

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

OC(CN(CCN(CCN(CCN(C1)CC(O)=O)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N=C=S)=O

Molecular Formula

C24H33N5O8S

Molecular Weight

551.61

References & Citations

[1]Xu L, et al. Evaluation of novel DOTA-based linkers for improved targeted radiotherapy delivery to solid tumors[J]. 2024.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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