Petromurin C
Petromurin C is a bisindolylbenzenoid compound isolated from the ascostromata of Petromycesmuricatus. Petromurin C induces protective autophagy and apoptosis in FLT3-ITD-positive AML[1][2].
Product Specifications
CAS Number
194608-29-2
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/petromurin-c.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C(OC)=C(C(C2=CNC3=C2C=CC=C3)=C1OC)OC)C4=CNC5=C4C=C(C=C5)O
Molecular Formula
C26H24N2O5
Molecular Weight
444.48
References & Citations
[1]Mikiko Ooike, et al. Bisindolylbenzenoids from ascostromata of Petromycesmuricatus.|[2]Ha YN, et al. Petromurin C Induces Protective Autophagy and Apoptosis in FLT3-ITD-Positive AML: Synergy with Gilteritinib. Mar Drugs. 2020;18 (1) :57.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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