(24S) -24,25-Dihydroxyvitamin D3

(24S) -24,25-Dihydroxyvitamin D3 ((24S) -24,25-Dihydroxycholecalciferol) is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs.

Product Specifications

CAS Number

[55700-58-8]

Product Name Alternative

(24S) -24,25-Dihydroxycholecalciferol

UNSPSC

12352211

Hazard Statement

H300

Target

VD/VDR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/_24S_-24,25-Dihydroxyvitamin-D3.html

Purity

98.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=C1/C(C[C@@H](O)CC1)=C\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)CC[C@H](O)C(C)(C)O)CC3

Molecular Formula

C27H44O3

Molecular Weight

416.64

Precautions

H300

References & Citations

[1]Yamada S, Ino E, Takayama H et al. Differences in the side-chain metabolism of vitamin D3 between chickens and rats. Proc Natl Acad Sci U S A. 1985 Nov;82 (22) :7485-9.|[2]Kobayashi N, Higashi T, Saito K et al. Specificity of polyclonal antibodies raised against a novel 24,25-dihydroxyvitamin D3-bovine serum albumin conjugant linked through the C-11alpha or C-3 position. J Steroid Biochem Mol Biol. 1997 May;62 (1) :79-87.|[3]Larsson D, Nemere I, Sundell K. Putative basal lateral membrane receptors for 24,25-dihydroxyvitamin D (3) in carp and Atlantic cod enterocytes: characterization of binding and effects on intracellular calcium regulation. J Cell Biochem. 2001 Aug 1-9;83 (2) :171-86.|[4]Nemere I, Yazzie-Atkinson D, Johns DO, Larsson D. Biochemical characterization and purification of a binding protein for 24,25-dihydroxyvitamin D3 from chick intestine. J Endocrinol. 2002 Jan;172 (1) :211-9.