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FOG-001

FOG-001 is a potent β-catenin/TCF interaction inhibitor (IC50 < 50 nM) that suppresses Wnt signaling, inhibits proliferation, and induces cell cycle arrest in vitro. It demonstrates significant anti-tumor efficacy in a COLO320DM colon cancer xenograft model, making it a valuable tool for studying oncogenic Wnt pathway mechanisms and therapeutic strategies.

Product Specifications

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Molecular Weight

2076.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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