FOG-001
FOG-001 is a potent β-catenin/TCF interaction inhibitor (IC50 < 50 nM) that suppresses Wnt signaling, inhibits proliferation, and induces cell cycle arrest in vitro. It demonstrates significant anti-tumor efficacy in a COLO320DM colon cancer xenograft model, making it a valuable tool for studying oncogenic Wnt pathway mechanisms and therapeutic strategies.
Product Specifications
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Molecular Weight
2076.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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