SRT3109
SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.
Product Specifications
CAS Number
[1204707-71-0]
Product Name Alternative
AZD-5122
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/srt3109.html
Concentration
10mM
Purity
99.68
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC1=C(F)C=CC=C1CSC2=NC(NS(=O)(N3CCC3)=O)=CC(N[C@@H]([C@@H](O)CO)C)=N2
Molecular Formula
C18H23F2N5O4S2
Molecular Weight
475.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases. WO2010007427A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CXCR2
Available Sizes
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