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SRT3109

SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.

Product Specifications

CAS Number

[1204707-71-0]

Product Name Alternative

AZD-5122

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CXCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/srt3109.html

Concentration

10mM

Purity

99.68

Solubility

DMSO : ≥ 100 mg/mL

Smiles

FC1=C(F)C=CC=C1CSC2=NC(NS(=O)(N3CCC3)=O)=CC(N[C@@H]([C@@H](O)CO)C)=N2

Molecular Formula

C18H23F2N5O4S2

Molecular Weight

475.53

Precautions

H302, H315, H319, H335

References & Citations

[1]Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases. WO2010007427A1

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

CXCR2

Available Sizes

Curated Selection

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