15 (R) -Lipoxin A4
15 (R) -Lipoxin A4 (15-epi-LXA4) is a STAT-6 activator and a lipid-derived lipoxin-type specialized pro-resolving mediator (SPM) that plays a role in promoting inflammation resolution and regulating immune cell function. 15 (R) -Lipoxin A4 can improve the phagocytic function of microglia and exhibits anti-inflammatory activity. In Alzheimer's disease (AD) mouse models, 15 (R) -Lipoxin A4 improves AD-like pathology. 15 (R) -Lipoxin A4 holds potential for use in inflammation and neurodegenerative disease research[1].
Product Specifications
CAS Number
171030-11-8
Product Name Alternative
15-epi-LXA4
UNSPSC
12352211
Hazard Statement
H225, H319
Target
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/15-r-lipoxin-a4.html
Concentration
283.71 μM * 250 μL in Ethanol
Purity
98.3
Smiles
CCCCC[C@@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O
Molecular Formula
C20H32O5
Molecular Weight
352.47
Precautions
H225, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT6
Available Sizes
Frequently Asked Questions
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