ER degrader 9
Product Specifications
UNSPSC Description
ER degrader 9 (compound 1), a bifunctional molecular glue, is a potent estrogen receptor (ER) degrader with a DC50 of ≤10 nM in MCF-7 cells. ER degrader 9 can be used for the research of breast cancer[1].
Target Antigen
Estrogen Receptor/ERR; Molecular Glues
Type
Reference compound
Related Pathways
PROTAC;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/er-degrader-9.html
Smiles
CC(C)(/C=C(C(N1CCN(CC1)CC2CCN(CC2)C3=CC=C(C=C3)[C@H]4[C@H](CCC5=CC(O)=CC=C54)C6=CC=CC=C6)=O)/C#N)C
Molecular Weight
616.83
References & Citations
[1]Andrea TESTA, et al. Bifunctional molecules for targeted protein degradation. WO2023242598A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163812/ER-degrader-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163812/
Clinical Information
No Development Reported
CAS Number
3023359-75-0
Curated Selection
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