MMP2-IN-1

MMP2-IN-1 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 μM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis[1].

Product Specifications

CAS Number

[2764598-01-6]

UNSPSC

12352005

Target

Apoptosis; MMP

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp2-in-1.html

Purity

99.24

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1COC2(C=CC(C=C2)=O)N1S(=O)(C3=CC=C(C)C=C3)=O

Molecular Formula

C15H13NO5S

Molecular Weight

319.33

References & Citations

[1]Chen C, Luo Y, Yin H, et al. Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones. Bioorg Med Chem. 2022;60:116626.