TDP1 Inhibitor-3
TDP1 Inhibitor-3 (Compound 4E) is a (TDP1) inhibitor with an IC50 value of 0.63 μM[1].
Product Specifications
CAS Number
[3074962-67-4]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tdp1-inhibitor-3.html
Purity
98.10
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[H][C@@]12CC[C@@]3(C[C@](CSC4=NC5=C(S4)C=CC=C5)(CC[C@@]3([C@@]1([H])C[C@@H]([C@]6([C@@]2([H])CC[C@@H]6[C@@H](CCC(OC)=O)C)C)O)C)O)[H]
Molecular Formula
C33H47NO4S2
Molecular Weight
585.86
References & Citations
[1]Salomatina O V, et al. New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling[J]. Molecules, 2024, 29 (3) : 581.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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