FINO2

FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation[1].

Product Specifications

CAS Number

[869298-31-7]

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fino2.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OCCC1(C[C@](CC[C@H]2C(C)(C)C)(CC2)OO1)C

Molecular Formula

C15H28O3

Molecular Weight

256.38

References & Citations

[1]Gaschler MM, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14 (5) :507-515.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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