FINO2
Product Specifications
UNSPSC Description
FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation[1].
Target Antigen
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fino2.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OCCC1(C[C@](CC[C@H]2C(C)(C)C)(CC2)OO1)C
Molecular Weight
256.38
References & Citations
[1]Gaschler MM, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129457/FINO2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129457/FINO2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
869298-31-7
Available Sizes
Curated Selection
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