15 (S) -15-methyl Prostaglandin D2
15 (S) -15-methyl Prostaglandin D2 (15 (S) -15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15 (S) -15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2) .
Product Specifications
CAS Number
[85280-90-6]
Product Name Alternative
15 (S) -15-Methyl PGD2
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/15-s-15-methyl-prostaglandin-d2.html
Smiles
OC(CCC/C=C\C[C@@H]([C@H](C1)O)[C@H](C1=O)/C=C/[C@@](C)(O)CCCCC)=O
Molecular Formula
C21H34O5
Molecular Weight
366.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bundy, et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J. Med. Chem. 26 (6), 790-799 (1983) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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