BX-513 (hydrochloride)

BX-513 hydrochloride (VUF 2274 hydrochloride) is a novel inverse agonists acting on human cytomegalovirus (HCMV) -encoded receptor US28 with the IC50 of 4.9 μM. BX-513 hydrochloride can be used for study of viral infection[1].

Product Specifications

CAS Number

[1216540-18-9]

Product Name Alternative

VUF2274 (hydrochloride)

UNSPSC

12352005

Target

CMV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bx-513-hydrochloride.html

Purity

99.94

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.[H]Cl

Molecular Formula

C28H30Cl2N2O

Molecular Weight

481.46

References & Citations

[1]Hulshof JW, et al. Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28. Bioorg Med Chem. 2006;14 (21) :7213-7230.