BP-1-108
Product Specifications
UNSPSC Description
BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer[1].
Target Antigen
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bp-1-108.html
Smiles
O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(C)C=C(C)C=C4C)=O)=O)C=C1O
Molecular Weight
578.72
References & Citations
[1]Page, et al. "Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity." Journal of medicinal chemistry 55.3 (2012): 1047-1055.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125151/BP-1-108-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125151/
Clinical Information
No Development Reported
CAS Number
1334492-85-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
