STL001
Product Specifications
UNSPSC Description
STL001 is potent and selective FOXM1 inhibitor. STL001 induces the translocation of nuclear FOXM1 to the cytoplasm and promotes its autophagic degradation. STL001 sensitizes human cancers to a broad-spectrum of cancer therapies[1].
Target Antigen
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stl001.html
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CO1)OC2=CC(C3=NN(C=C3)C4=NC(NC5=CC=CC=C5)=NC(N6CCOCC6)=N4)=CC=C2
Molecular Weight
509.52
References & Citations
[1]Sanjeev Raghuwanshi, et al. Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies. Cell Death Discov. 2024 May 2;10(1):211.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158420/STL001-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158420/STL001-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3047493-70-6
Available Sizes
Curated Selection
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