STL001
STL001 is potent and selective FOXM1 inhibitor. STL001 induces the translocation of nuclear FOXM1 to the cytoplasm and promotes its autophagic degradation. STL001 sensitizes human cancers to a broad-spectrum of cancer therapies[1].
Product Specifications
CAS Number
[3047493-70-6]
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stl001.html
Purity
99.81
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CO1)OC2=CC(C3=NN(C=C3)C4=NC(NC5=CC=CC=C5)=NC(N6CCOCC6)=N4)=CC=C2
Molecular Formula
C27H23N7O4
Molecular Weight
509.52
References & Citations
[1]Sanjeev Raghuwanshi, et al. Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies. Cell Death Discov. 2024 May 2;10 (1) :211.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15217088 1 Vial
Lentiviral mouse Ppib shRNA (UAS) - Lentiviral mousePpib shRNA (UAS, GFP) (25)
Ask
View Details 
RC231069L4V 200 µL
MKRN2OS (NM_001195279) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details MBS6383403-01 0.1 mL
Junctional Adhesion Molecule 1 (JAM-1, CD321, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAMA, JCAM, KAT, Platelet Adhesion Molecule 1, PAM1, Platelet F11 Receptor, UNQ264/PRO301) (HRP)
Ask
View Details MBS6383403-02 5x 0.1 mL
Junctional Adhesion Molecule 1 (JAM-1, CD321, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAMA, JCAM, KAT, Platelet Adhesion Molecule 1, PAM1, Platelet F11 Receptor, UNQ264/PRO301) (HRP)
Ask
View Details MBS6380886-01 0.1 mL
HDAC3 (Histone Deacetylase 3, HD3, RPD3-2, SMAP45, RPD3) (MaxLight 490)
Ask
View Details