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Leptomycin B

Antifungal antibiotic, inhibitor of the nuclear export of proteins

Product Specifications

Product Name Alternative

(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-((2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid

Purity

0.98

Form

<41°C Solid, >44°C Liquid

Solubility

≥98.8 mg/mL in DMSO; ≥90.6 mg/mL in EtOH; insoluble in H2O

Smiles

O[C@@H]([C@H](C)C([C@@H](/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@@H]([C@H](C=C1)C)OC1=O)C)=O)[C@@H](C)C/C(C)=C/C(O)=O

Molecular Formula

C33H48O6

Molecular Weight

540.74

Shipping Conditions

Blue ice

Storage Conditions

Desiccate at -20°C.

CAS Number

87081-35-4

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